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      Unlocking drug repurposing clinical trials: resources for investigators

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            Abstract

            Drug repurposing has recently been recognized for its potential to improve the process of drug development. To facilitate the implementation of drug repurposing in clinical research, resources to support investigators in conducting Phase II repurposing trials are under development, which will be presented as part of a comprehensive platform. Innovative clinical trial designs and mechanism-based network pharmacology are also emphasized.

            Content

            Author and article information

            Journal
            DrugRxiv
            REPO4EU
            7 October 2024
            Affiliations
            [1 ] 3D-PharmXchange;
            Author notes
            Author information
            https://orcid.org/0009-0004-1063-3482
            Article
            10.58647/DRUGARXIV.PR000016.v1
            119a0679-b6e3-4a78-be79-4511ec54e5a7

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            History
            : 7 October 2024
            Categories

            Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
            Life sciences
            Drug repurposing,Innovative clinical trial designs,Investigator initiated trials,Mechanism-based network pharmacology,Phase II clinical trials

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