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      Using click chemistry to access mono- and ditopic β-cyclodextrin hosts substituted by chiral amino acids.

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          Abstract

          A wide range of chiral mono- and ditopic cyclodextrin-based receptors have been synthesized by CuI-catalyzed azide-alkyne cycloaddition starting from mono-6-azido-β-cyclodextrin and chiral amino acids. Of interest, microwaves proved very efficient to access a wide range of ditopic β-cyclodextrin receptors with quantitative yields.

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          Author and article information

          Journal
          Carbohydr. Res.
          Carbohydrate research
          Elsevier BV
          1873-426X
          0008-6215
          Feb 01 2011
          : 346
          : 2
          Affiliations
          [1 ] Univ Lille Nord de France, F-59000 Lille, France.
          Article
          S0008-6215(10)00508-2
          10.1016/j.carres.2010.11.024
          21185553
          a4089b93-2bcc-4c33-b477-6292000d08a6
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