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      Manhattan Projects for Preventive Medicine

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            Abstract

            In this opinion article, we argue that the requisite scientific knowledge and technological capabilities to elucidate the fundamental causes of chronic diseases - and to develop strategies for their prevention, reversal, and cure - already exist today. However, to implement this vision, a transformative shift in the scientific approach is required. We advocate for a new way to conduct science, inspired by the organizational structure, interdisciplinary synergy, and operational excellence of the Manhattan Project (not its goal of developing a weapon). This model will overcome the current fragmentation of the scientific efforts, which are dispersed across tens of thousands of isolated projects, each with distinct objectives, datasets, methodologies, and analyses. It will also not be distracted and disoriented by the current incentive structure in academic research, which focuses on publications. By adopting the collaborative and goal-oriented framework of the Manhattan Project, humanity can refocus the scientific efforts to effectively confront and consign chronic diseases to the annals of history.

            Content

            Author and article information

            Journal
            DrugRxiv
            REPO4EU
            24 July 2024
            Affiliations
            [1 ] Viome Life Sciences;
            [2 ] The LivLyme Foundation;
            [3 ] Vicebio Limite;
            [4 ] Viome Life Sciences and AdventHealth;
            [5 ] VitalizeDx;
            [6 ] Intracell Research Group;
            [7 ] The Doctor's Kitchen;
            Author notes
            Author information
            https://orcid.org/0000-0002-0531-6755
            Article
            10.58647/DRUGARXIV.PR000015.v1
            cac8ff84-b50a-4d42-98ba-abcdf89643bd

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            History
            : 24 July 2024
            Categories

            Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
            Quantitative & Systems biology,Life sciences
            systems biology,preventive medicine,chronic diseases,eradication

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