Accelerating Drug Develoment: Unleashing the Power of Drug Repurposing

Drug repurposing, also called drug repositioning, reprofiling or retasking, is the process of identifying a new use for an existing medicine/active substance outside the scope of the original indication(s). It includes new therapeutic uses for existing medicines, different formulations of the same medicine, and/or creating new combinations of medicines or medicines with medical devices.

Drug repurposing has recently attracted much attention as it promises faster timelines, lower costs and less risk compared to new drug development.

Content

Author and article information

Journal

Title: DrugRxiv

Publisher: REPO4EU

Publication date (Electronic preprint): 30 April 2024

Affiliations

[1 ] Regulatory Affairs Department, 3D-PharmXchange, Tilburg, The Netherlands;

Author notes

[* ]Email: bianca@ 1234563d-pxc.com .

Author information

Bianca Pauly https://orcid.org/0009-0000-3034-956X

Article

DOI: 10.58647/DRUGARXIV.PR000012.v1

SO-VID: a6a0f61d-9c64-449e-879b-769c5ad21eb8

License:

This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

History

Date received : 30 April 2024

References

Asker-Hagelberg Charlotte, Boran Tomas, Bouygues Christelle, Eskola Sini Marika, Helmle Laszlo, Hernández César, Houýez François, Lee Helen, Lingri Dimitra D., Louette Laurent, Meheus Lydie, Penninckx Wim, Stepniewska Beata. Repurposing of Medicines in the EU: Launch of a Pilot Framework. Frontiers in Medicine. Vol. 8:2022. Frontiers Media SA. [Cross Ref]
Zhang Zhe, Zhou Li, Xie Na, Nice Edouard C., Zhang Tao, Cui Yongping, Huang Canhua. Overcoming cancer therapeutic bottleneck by drug repurposing. Signal Transduction and Targeted Therapy. Vol. 5(1)2020. Springer Science and Business Media LLC. [Cross Ref]
Ahmed Faheem, Soomro Afaque Manzoor, Chethikkattuveli Salih Abdul Rahim, Samantasinghar Anupama, Asif Arun, Kang In Suk, Choi Kyung Hyun. A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19. Biomedicine & Pharmacotherapy. Vol. 153:2022. Elsevier BV. [Cross Ref]

Comments

Comment on this article

[1] Asker-Hagelberg Charlotte, Boran Tomas, Bouygues Christelle, Eskola Sini Marika, Helmle Laszlo, Hernández César, Houýez François, Lee Helen, Lingri Dimitra D., Louette Laurent, Meheus Lydie, Penninckx Wim, Stepniewska Beata. Repurposing of Medicines in the EU: Launch of a Pilot Framework. Frontiers in Medicine. Vol. 8:2022. Frontiers Media SA. [Cross Ref]

[2] Zhang Zhe, Zhou Li, Xie Na, Nice Edouard C., Zhang Tao, Cui Yongping, Huang Canhua. Overcoming cancer therapeutic bottleneck by drug repurposing. Signal Transduction and Targeted Therapy. Vol. 5(1)2020. Springer Science and Business Media LLC. [Cross Ref]

[3] Ahmed Faheem, Soomro Afaque Manzoor, Chethikkattuveli Salih Abdul Rahim, Samantasinghar Anupama, Asif Arun, Kang In Suk, Choi Kyung Hyun. A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19. Biomedicine & Pharmacotherapy. Vol. 153:2022. Elsevier BV. [Cross Ref]