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      Concerns surrounding the frequent exposure to QAC

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            Abstract

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            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            22 October 2024
            Affiliations
            [1 ] University of California, Davis ( https://ror.org/05rrcem69)
            Author notes
            Author information
            https://orcid.org/0009-0009-6906-8613
            Article
            10.14293/PR2199.001203.v1
            222d37e8-8cd0-4231-ac13-41fcf77935b8

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

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            : 22 October 2024
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            Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
            Environmental chemistry,Chemical & Environmental safety,Environmental studies

            References

            1. Jennings Megan C., Minbiole Kevin P. C., Wuest William M.. Quaternary Ammonium Compounds: An Antimicrobial Mainstay and Platform for Innovation to Address Bacterial Resistance. ACS Infectious Diseases. Vol. 1(7):288–303. 2015. American Chemical Society (ACS). [Cross Ref]

            2. Zheng Guomao, Schreder Erika, Sathyanarayana Sheela, Salamova Amina. The first detection of quaternary ammonium compounds in breast milk: Implications for early-life exposure. Journal of Exposure Science & Environmental Epidemiology. Vol. 32(5):682–688. 2022. Springer Science and Business Media LLC. [Cross Ref]

            3. Ogilvie B.H., Solis-Leal A., Lopez J.B., Poole B.D., Robison R.A., Berges B.K.. Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2. Journal of Hospital Infection. Vol. 108:142–145. 2021. Elsevier BV. [Cross Ref]

            4. Merchel Piovesan Pereira Beatriz, Tagkopoulos Ilias. Benzalkonium Chlorides: Uses, Regulatory Status, and Microbial Resistance. Applied and Environmental Microbiology. Vol. 85(13)2019. American Society for Microbiology. [Cross Ref]

            5. Zheng Guomao, Webster Thomas F., Salamova Amina. Quaternary Ammonium Compounds: Bioaccumulation Potentials in Humans and Levels in Blood before and during the Covid-19 Pandemic. Environmental Science & Technology. Vol. 55(21):14689–14698. 2021. American Chemical Society (ACS). [Cross Ref]

            6. Lineback Caitlinn B., Nkemngong Carine A., Wu Sophie Tongyu, Li Xiaobao, Teska Peter J., Oliver Haley F.. Hydrogen peroxide and sodium hypochlorite disinfectants are more effective against Staphylococcus aureus and Pseudomonas aeruginosa biofilms than quaternary ammonium compounds. Antimicrobial Resistance & Infection Control. Vol. 7(1)2018. Springer Science and Business Media LLC. [Cross Ref]

            7. Zhang Shanshan, Palazuelos-Munoz Sarah, Balsells Evelyn M., Nair Harish, Chit Ayman, Kyaw Moe H.. Cost of hospital management of Clostridium difficile infection in United States—a meta-analysis and modelling study. BMC Infectious Diseases. Vol. 16(1)2016. Springer Science and Business Media LLC. [Cross Ref]

            8. Gerding Dale N., Muto Carlene A., Owens, Jr. Robert C.. Measures to Control and Prevent<i>Clostridium difficile</i>Infection. Clinical Infectious Diseases. Vol. 46(s1)2008. Oxford University Press (OUP). [Cross Ref]

            9. Schrank Cassandra L., Minbiole Kevin P. C., Wuest William M.. Are Quaternary Ammonium Compounds, the Workhorse Disinfectants, Effective against Severe Acute Respiratory Syndrome-Coronavirus-2? ACS Infectious Diseases. Vol. 6(7):1553–1557. 2020. American Chemical Society (ACS). [Cross Ref]

            10. Hora Priya I., Pati Sarah G., McNamara Patrick J., Arnold William A.. Increased Use of Quaternary Ammonium Compounds during the SARS-CoV-2 Pandemic and Beyond: Consideration of Environmental Implications. Environmental Science &amp; Technology Letters. Vol. 7(9):622–631. 2020. American Chemical Society (ACS). [Cross Ref]

            11. Xian Yanping, Dong Hao, Wu Yuluan, Guo Xindong, Hou Xiangchang, Wang Bin. QuEChERS-based purification method coupled to ultrahigh performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) to determine six quaternary ammonium compounds (QACs) in dairy products. Food Chemistry. Vol. 212:96–103. 2016. Elsevier BV. [Cross Ref]

            12. Zhang Chang, Cui Fang, Zeng Guang-ming, Jiang Min, Yang Zhong-zhu, Yu Zhi-gang, Zhu Meng-ying, Shen Liu-qing. Quaternary ammonium compounds (QACs): A review on occurrence, fate and toxicity in the environment. Science of The Total Environment. Vol. 518-519:352–362. 2015. Elsevier BV. [Cross Ref]

            13. Hrubec Terry C., Seguin Ryan P., Xu Libin, Cortopassi Gino A., Datta Sandipan, Hanlon Alexandra L., Lozano Alicia J., McDonald Valerie A., Healy Claire A., Anderson Tyler C., Musse Najaha A., Williams Richard T.. Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure. Toxicology Reports. Vol. 8:646–656. 2021. Elsevier BV. [Cross Ref]

            14. Zheng Guomao, Filippelli Gabriel M., Salamova Amina. Increased Indoor Exposure to Commonly Used Disinfectants during the COVID-19 Pandemic. Environmental Science &amp; Technology Letters. Vol. 7(10):760–765. 2020. American Chemical Society (ACS). [Cross Ref]

            15. Herron Josi M, Hines Kelly M, Tomita Hideaki, Seguin Ryan P, Cui Julia Yue, Xu Libin. Multiomics Investigation Reveals Benzalkonium Chloride Disinfectants Alter Sterol and Lipid Homeostasis in the Mouse Neonatal Brain. Toxicological Sciences. Vol. 171(1):32–45. 2019. Oxford University Press (OUP). [Cross Ref]

            16. Kwon Doyoung, Kwon Jung-Taek, Lim Yeon-Mi, Shim Ilseob, Kim Eunji, Lee Doo-Hee, Yoon Byung-Il, Kim Pilje, Kim Hyun-Mi. Inhalation toxicity of benzalkonium chloride and triethylene glycol mixture in rats. Toxicology and Applied Pharmacology. Vol. 378:2019. Elsevier BV. [Cross Ref]

            17. Herron Josi, Reese Rosalyn C., Tallman Keri A., Narayanaswamy Rohini, Porter Ned A., Xu Libin. Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis. Toxicological Sciences. Vol. 151(2):261–270. 2016. Oxford University Press (OUP). [Cross Ref]

            18. Yegin Yagmur, Oh Jun K., Akbulut Mustafa, Taylor Thomas. Cetylpyridinium chloride produces increased zeta-potential on Salmonella Typhimurium cells, a mechanism of the pathogen’s inactivation. npj Science of Food. Vol. 3(1)2019. Springer Science and Business Media LLC. [Cross Ref]

            19. Datta Sandipan, Baudouin Christophe, Brignole-Baudouin Francoise, Denoyer Alexandre, Cortopassi Gino A.. The Eye Drop Preservative Benzalkonium Chloride Potently Induces Mitochondrial Dysfunction and Preferentially Affects LHON Mutant Cells. Investigative Opthalmology &amp; Visual Science. Vol. 58(4)2017. Association for Research in Vision and Ophthalmology (ARVO). [Cross Ref]

            20. Melin Vanessa E., Melin Travis E., Dessify Brian J., Nguyen Christina T., Shea Caroline S., Hrubec Terry C.. Quaternary ammonium disinfectants cause subfertility in mice by targeting both male and female reproductive processes. Reproductive Toxicology. Vol. 59:159–166. 2016. Elsevier BV. [Cross Ref]

            21. Datta Sandipan, He Guochun, Tomilov Alexey, Sahdeo Sunil, Denison Michael S., Cortopassi Gino. <i>In Vitro</i> Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride. Environmental Health Perspectives. Vol. 125(8)2017. Environmental Health Perspectives. [Cross Ref]

            22. Hrubec Terry C., Melin Vanessa E., Shea Caroline S., Ferguson Elizabeth E., Garofola Craig, Repine Claire M., Chapman Tyler W., Patel Hiral R., Razvi Reza M., Sugrue Jesse E., Potineni Haritha, Magnin‐Bissel Geraldine, Hunt Patricia A.. Ambient and Dosed Exposure to Quaternary Ammonium Disinfectants Causes Neural Tube Defects in Rodents. Birth Defects Research. Vol. 109(14):1166–1178. 2017. Wiley. [Cross Ref]

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