The Algorithm: Trans-Jugular Versus Percutaneous Liver Biopsy: A Methodology for Technique Selection

This paper presents a detailed analysis of transjugular liver biopsy (TJLB) and percutaneous liver biopsy (PLB),examining their respective clinical strengths and weaknesses. The discussion highlights the distinct advantage of TJLBin measuring hepatic venous pressure gradients (HVPG), a critical factor in assessing the severity of liver disease. Thepaper delves into the procedural aspects, safety profiles, diagnostic efficacy, and specific clinical scenarios where eachtechnique is preferable. Special attention is given to the role of HVPG measurements obtained via TJLB in evaluatingportal hypertension and its implications in liver disease management. The analysis also considers the impact of patientspecificfactors such as coagulopathy and ascites on the choice of biopsy technique. By contrasting the technicalnuances, risks, and benefits of TJLB and PLB, this paper aims to guide clinicians in making informed decisions tailoredto individual patient needs in the context of liver disease diagnosis and management.