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      Inquiry and Computer Program Onko-Online: 25 Years of Clinical Registry for Breast Cancer at the University Medical Centre Maribor

      research-article
      1 , 2 , , M.D., Ph.D., * , 1 , 2
      Radiology and Oncology
      Sciendo
      clinical registry, computer program, breast cancer

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          Abstract

          Background

          High-quality routine care data collected in the clinical registry play a significant role in improving the management of cancer patients. Clinical cancer registries record important data in the course of cancer diagnosis, treatment, follow-up and survival. Analyses of such comprehensive data pool make it possible to improve the quality of patients care and compare with other health care providers.

          Methods

          The first inquiry at the Department of Gynaecologic and Breast Oncology of the then General Hospital Maribor to follow breast cancer patients has been introduced in 1994. Based on our experience and new approaches in breast cancer treatment, the context of inquiry has been changed and extended to the present form, which served as a model for developing a relevant computer programme named Onko-Online in 2014.

          Results

          During the 25-year period, we collected data from about 3,600 breast cancer patients. The computer program Onko-Online allowed for quick and reliable collection, processing and analysis of 167 different data of breast cancer patients including general information, medical history, diagnostics, treatment, and follow-up.

          Conclusions

          The clinical registry for breast cancer Onko-Online provides data that help us to improve diagnostics and treatment of breast cancer patients, organize the daily practice and to compare the results of our treatment to the national and international standards. A limitation of the registry is the potentially incomplete or incorrect data input by different healthcare providers, involved in the treatment of breast cancer patients.

          Related collections

          Most cited references27

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          Contemporary Hormonal Contraception and the Risk of Breast Cancer

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            Links between Alcohol Consumption and Breast Cancer: A Look at the Evidence

            Alcohol consumption by adult women is consistently associated with risk of breast cancer. Several questions regarding alcohol and breast cancer need to be addressed. Menarche to first pregnancy represents a window of time when breast tissue is particularly susceptible to carcinogens. Youth alcohol consumption is common in the USA, largely in the form of binge drinking and heavy drinking. Whether alcohol intake acts early in the process of breast tumorigenesis is unclear. This review aims to focus on the influences of timing and patterns of alcohol consumption and the effect of alcohol on intermediate risk markers. We also review possible mechanisms underlying the alcohol-breast cancer association.
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              Impact on survival of early detection of isolated breast recurrences after the primary treatment for breast cancer: a meta-analysis.

              The purpose was to establish the impact on survival of early detection of a local recurrence of breast cancer as compared to late detection. A meta-analysis was carried out using Cochrane review manager software (RevMan version 4.2). Studies were included if women were treated for primary breast cancer without evidence of distant metastasis at primary diagnosis and if these concerned routine follow-up strategies focusing on the early detection of curable recurrences. Data regarding the risk for death were derived from each study. Multi level models were used to study heterogeneity by using MLWin. Thirteen studies concerning 2,263 patients were included. Early detection of breast cancer recurrences during follow-up gave a significantly better survival as compared to late detected recurrences (HR: 1.68 (95% CI: 1.48-1.91)). Survival was better when the recurrence was found by mammography instead of physical examination or in patients without symptoms as compared to those with symptoms (HR: 2.44 (95% CI: 1.78-3.35); HR: 1.56 (95% CI: 1.36-1.79), respectively). If all breast cancer recurrences would be detected earlier, that 5-8 deaths (i.e. an absolute reduction in mortality of 17-28%) would be avoided by performing routine follow-up during a 10 year-period for 1,000 breast cancer patients. These data support the hypothesis that detection of isolated loco-regional or contra-lateral breast cancer recurrences in patients without symptoms has beneficial impact on survival of breast cancer patients when compared to late symptomatic detection.
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                Author and article information

                Journal
                Radiol Oncol
                Radiol Oncol
                raon
                raon
                Radiology and Oncology
                Sciendo
                1318-2099
                1581-3207
                September 2019
                24 September 2019
                : 53
                : 3
                : 348-356
                Affiliations
                [1 ]University Medical Centre Maribor , Maribor, Slovenia
                [2 ]Faculty of Medicine, University of Maribor , Maribor, Slovenia
                Author notes
                [* ] Prof. Iztok Takač, M.D., Ph.D., Adviser; Division of Gynaecology and Perinatology, Maribor University Medical Centre, Ljubljanska 5, 2000 Maribor, Slovenia. Phone: +386 2 321 2445 iztok.takac@ 123456ukc-mb.si
                Article
                raon-2019-0043
                10.2478/raon-2019-0043
                6765156
                31553707
                f55cba2b-7a8d-4de6-aece-07eb420dceb0
                © 2019 Darja Arko, Iztok Takac, published by Sciendo

                This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

                History
                : 17 February 2019
                : 16 May 2019
                Page count
                Pages: 9
                Categories
                Research Article

                Oncology & Radiotherapy
                clinical registry,computer program,breast cancer
                Oncology & Radiotherapy
                clinical registry, computer program, breast cancer

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