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      Modellierte Individualentwicklung. Humanembryologische Praktiken an der Universität Göttingen in der zweiten Hälfte des 20. Jahrhunderts Translated title: Modelled Development. Practices of Human Embryology at Göttingen University in the Second Half of the Twentieth Century

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          Abstract

          Die Humanembryologische Dokumentationssammlung Blechschmidt, entstanden an der Universität Göttingen im Zeitraum von 1942 bis etwa 1970, stellt eine einmalige Kombination histologischer Schnittserien menschlicher Embryonen und darauf aufbauender, großformatiger und öffentlich zugänglicher Modelle dar. Nicht nur erfolgte diese Sammlungsgründung für die Disziplin der Humanembryologie erstaunlich spät, sondern ist auch in einer zweiten Hinsicht bemerkenswert: Während an anderen Standorten Modelle primär als Forschungsobjekte verstanden wurden und mit einem Lehreinsatz eine Umnutzung stattfand, war für den Göttinger Embryologen Erich Blechschmidt (1904–1992) von Beginn an ein pädagogischer Impetus maßgeblich. Im Beitrag werden die eigenwilligen Merkmale der Blechschmidt’schen Unternehmung vor ihrem disziplinären Hintergrund herausgearbeitet. Der Schwerpunkt liegt dabei auf den beiden für die Humanembryologie zentralen Praktiken des Sammelns und Modellierens und den dadurch in Göttingen geschaffenen Objektbeständen. Diese waren schon im Entstehungsprozess von einem besonderen Spannungsverhältnis von Individualität und Universalität geprägt, das sich auch in der späteren Nutzung der Sammlung spiegelt. Diese führt durch eine spezifische Individualisierung zuvor anonym gemachter Präparate weit aus der ursprünglichen fachwissenschaftlich-anatomischen Bestimmung in die breite gesellschaftliche Debatte um den ethischen Status menschlicher Embryonen und den Schwangerschaftsabbruch.

          Translated abstract

          The Human Embryology Collection at the Centre of Anatomy Göttingen, created between 1942 and 1970, represents a unique interrelation of histological sectional series of human embryos and large-format physical models open to the public based on them. The collection was established long after the heyday of human embryology. It is also remarkable in another aspect: while usually models within the discipline are considered research objects, Göttingen embryologist Erich Blechschmidt (1904–1992) based his understanding on a pedagogical impetus. The article highlights the distinctive and unconventional features of Blechschmidt’s undertaking against its disciplinary background. My focus lies on the two practices that are central to human embryology—collecting and modelling—, as well as the derived collection stocks. The special tension between individuality and universality that already characterized the process of their creation is also reflected in the later use of the collection. This tension allowed Blechschmidt to utilize the models in embryological research and anatomical teaching as well as in the broad social debate on abortion and the ethical status of human embryos.

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          Producing Development: The Anatomy of Human Embryos and the Norms of Wilhelm His

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            A history of normal plates, tables and stages in vertebrate embryology.

            Developmental biology is today unimaginable without the normal stages that define standard divisions of development. This history of normal stages, and the related normal plates and normal tables, shows how these standards have shaped and been shaped by disciplinary change in vertebrate embryology. The article highlights the Normal Plates of the Development of the Vertebrates edited by the German anatomist Franz Keibel (16 volumes, 1897-1938). These were a major response to problems in the relations between ontogeny and phylogeny that amounted in practical terms to a crisis in staging embryos, not just between, but (for some) also within species. Keibel's design adapted a plate by Wilhelm His and tables by Albert Oppel in order to go beyond the already controversial comparative plates of the Darwinist propagandist Ernst Haeckel. The project responded to local pressures, including intense concern with individual variation, but recruited internationally and mapped an embryological empire. Though theoretically inconclusive, the plates became standard laboratory tools and forged a network within which the Institut International d'Embryologie (today the International Society of Developmental Biologists) was founded in 1911. After World War I, experimentalists, led by Ross Harrison and Viktor Hamburger, and human embryologists, especially George Streeter at the Carnegie Department of Embryology, transformed Keibel's complex, bulky tomes to suit their own contrasting demands. In developmental biology after World War II, normal stages-reduced to a few journal pages-helped domesticate model organisms. Staging systems had emerged from discussions that questioned the very possibility of assigning an embryo to a stage. The historical issues resonate today as developmental biologists work to improve and extend stage series, to make results from different laboratories easier to compare and to take individual variation into account.
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              The Kyoto Collection of Human Embryos and Fetuses: History and Recent Advancements in Modern Methods.

              The Kyoto Collection of Human Embryos and Fetuses, the largest collection of human embryos worldwide, was initiated in the 1960s, and the Congenital Anomaly Research Center of Kyoto University was established in 1975 for long-term storage of the collection and for the promotion of research into human embryonic and fetal development. Currently, the Kyoto Collection comprises approximately 45,000 specimens of human embryonic or fetal development and is renowned for the following unique characteristics: (1) the collection is considered to represent the total population of fetal specimens nationwide in Japan, (2) it comprises a large number of specimens with a variety of external malformations, and (3) for most specimens there are clinical and epidemiological data from the mothers and the pregnancies concerned. Therefore, the specimens have been used extensively for morphological studies and could potentially be used for epidemiological analysis. Recently, several new approaches such as DNA extraction from formalin-fixed specimens or geometric morphometrics have been adopted and it is to be expected that further technological advances will facilitate new studies on the specimens of the Kyoto Collection as well as of other human embryo collections worldwide. Permanent preservation of the Kyoto Collection is, therefore, of paramount importance so that it will continue to contribute to human embryological studies in the future.
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                Author and article information

                Contributors
                michael.markert@uni-goettingen.de
                Journal
                NTM
                NTM
                Ntm
                Springer International Publishing (Cham )
                0036-6978
                1420-9144
                6 October 2020
                6 October 2020
                2020
                : 28
                : 4
                : 481-517
                Affiliations
                GRID grid.7450.6, ISNI 0000 0001 2364 4210, Kunstgeschichtliches Seminar und Kunstsammlung, Professur für Materialität des Wissens, , Georg-August-Universität Göttingen, ; Friedländer Weg 2, 37085 Göttingen, Deutschland
                Article
                275
                10.1007/s00048-020-00275-3
                7588383
                33021678
                e9b09071-af53-421f-9ffe-cd2b76e4378f
                © The Author(s) 2020

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                History
                Funding
                Funded by: Georg-August-Universität Göttingen (1018)
                Categories
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                © Springer Nature Switzerland AG 2020

                History
                humanembryologie,forschungsmodell,hochschullehre,praktiken,materielle kultur,human embryology,research model,academic teaching,practices,material culture

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