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      Free radical-induced damage to DNA: mechanisms and measurement 1,2 1This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal. 2Guest Editor: Miral Dizdaroglu

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      Free Radical Biology and Medicine
      Elsevier BV

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          Mutagenesis by 8-oxoguanine: an enemy within.

          The presence of reactive oxygen species in cells ensures that the oxidatively damaged base 8-oxoguanine will be generated at high frequency in the DNA of all living organisms. DNA damage threatens genomic integrity: enzymes have evolved that protect prokaryotes and eukaryotes from the mutagenic effect of this ubiquitous lesion.
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            How Easily Oxidizable Is DNA? One-Electron Reduction Potentials of Adenosine and Guanosine Radicals in Aqueous Solution

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              Purine bases, nucleosides, and nucleotides: aqueous solution redox chemistry and transformation reactions of their radical cations and e- and OH adducts

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                Author and article information

                Journal
                Free Radical Biology and Medicine
                Free Radical Biology and Medicine
                Elsevier BV
                08915849
                June 2002
                June 2002
                : 32
                : 11
                : 1102-1115
                Article
                10.1016/S0891-5849(02)00826-2
                a9a6909f-ce52-4327-9439-6eb10419fb5b
                © 2002

                http://www.elsevier.com/tdm/userlicense/1.0/

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