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      A Holistic Digital Health Framework to Support Health Prevention Strategies in the First 1000 Days

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          Abstract

          The first 1000 days of a child’s life, spanning from the time of conception until 2 years of age, are a key period of laying down the foundations of optimum health, growth, and development across the lifespan. Although the role of health prevention programs targeting families and children in the first 1000 days of life is well recognized, investments in this key period are scarce, and the provision of adequate health care services is insufficient. The aim of this viewpoint is to provide a holistic digital health framework cocreated with policy makers, health care professionals, and families to support more effective efforts and health care programs dedicated to the first 1000 days of life as the first line of prevention. The framework provides recommendations for leveraging on behavioral intervention technology and digital therapeutics solutions augmented by artificial intelligence to support the effective deployment of health prevention programs to families. The framework also encourages the adoption of a citizen science approach to co-design and evolve the digital health interventions with all relevant stakeholders in a real-world research perspective.

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          Most cited references44

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          Developing and evaluating complex interventions: the new Medical Research Council guidance

          Evaluating complex interventions is complicated. The Medical Research Council's evaluation framework (2000) brought welcome clarity to the task. Now the council has updated its guidance
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            From ideas to efficacy: The ORBIT model for developing behavioral treatments for chronic diseases.

            Given the critical role of behavior in preventing and treating chronic diseases, it is important to accelerate the development of behavioral treatments that can improve chronic disease prevention and outcomes. Findings from basic behavioral and social sciences research hold great promise for addressing behaviorally based clinical health problems, yet there is currently no established pathway for translating fundamental behavioral science discoveries into health-related treatments ready for Phase III efficacy testing. This article provides a systematic framework for developing behavioral treatments for preventing and treating chronic diseases.
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              IDEAS (Integrate, Design, Assess, and Share): A Framework and Toolkit of Strategies for the Development of More Effective Digital Interventions to Change Health Behavior

              Developing effective digital interventions to change health behavior has been a challenging goal for academics and industry players alike. Guiding intervention design using the best combination of approaches available is necessary if effective technologies are to be developed. Behavioral theory, design thinking, user-centered design, rigorous evaluation, and dissemination each have widely acknowledged merits in their application to digital health interventions. This paper introduces IDEAS, a step-by-step process for integrating these approaches to guide the development and evaluation of more effective digital interventions. IDEAS is comprised of 10 phases (empathize, specify, ground, ideate, prototype, gather, build, pilot, evaluate, and share), grouped into 4 overarching stages: Integrate, Design, Assess, and Share (IDEAS). Each of these phases is described and a summary of theory-based behavioral strategies that may inform intervention design is provided. The IDEAS framework strives to provide sufficient detail without being overly prescriptive so that it may be useful and readily applied by both investigators and industry partners in the development of their own mHealth, eHealth, and other digital health behavior change interventions.
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                Author and article information

                Contributors
                Journal
                JMIR Pediatr Parent
                JMIR Pediatr Parent
                JPP
                pediatrics
                30
                JMIR Pediatrics and Parenting
                JMIR Publications (Toronto, Canada )
                2561-6722
                2025
                16 January 2025
                : 8
                : e55235
                Affiliations
                [1 ]departmentDigital Health Research , Fondazione Bruno Kessler , Via Sommarive 18, Trento, 38123, Italy, 39 0461 312 477
                [2 ]departmentCenter for Digital Health & Wellbeing , Fondazione Bruno Kessler , Trento, Italy
                Author notes
                SilviaGabrielliMSc, PhD, Digital Health Research, Fondazione Bruno Kessler, Via Sommarive 18, Trento, 38123, Italy, 39 0461 312 477; sgabrielli@ 123456fbk.eu

                None declared.

                Author information
                http://orcid.org/0000-0002-7080-0615
                http://orcid.org/0000-0002-5773-3876
                http://orcid.org/0000-0003-3471-2033
                Article
                55235
                10.2196/55235
                11756837
                39819823
                648b0b7c-9de9-404d-bef9-40f4e42b922b
                Copyright © Silvia Gabrielli, Oscar Mayora Ibarra, Stefano Forti. Originally published in JMIR Pediatrics and Parenting (https://pediatrics.jmir.org)

                This is an open-access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Pediatrics and Parenting, is properly cited. The complete bibliographic information, a link to the original publication on https://pediatrics.jmir.org, as well as this copyright and license information must be included.

                History
                : 06 December 2023
                : 14 June 2024
                : 26 October 2024
                Categories
                Viewpoints/Opinion Papers
                Viewpoints and Perspectives
                Parenting
                Viewpoints on and Experiences with Digital Technologies in Health
                Applications of AI
                Theoretical Frameworks and Concepts
                Theories, Models, and Frameworks in Human Factors
                Viewpoint

                digital health,digital therapeutics,behavioral intervention technology,prevention,citizen science,first 1000 days

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