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Abstract
<p class="first" id="P1">Most measures of cognitive function used in large-scale surveys
of older adults have
limited ability to detect subtle differences across cognitive domains, and
<tt>standard</tt> clinical instruments are impractical to administer in general surveys.
The Montreal
Cognitive Assessment (MoCA) can address this need, but has limitations in a survey
context. Therefore, we developed a survey-adaptation of the MoCA, called the MoCA-SA,
and describe its psychometric properties in a large national survey. Using a pretest
sample of older adults (n=120), we reduced MoCA administration time by 26%, developed
a model to accurately estimate full MoCA scores from the MoCA-SA, and tested the model
in an independent clinical sample (n=93). The validated 18-item MoCA-SA was then administered
to community-dwelling adults aged 62–91 as part of the National Social life Health
and Aging Project (NSHAP) Wave 2 sample (n=3,196). In NSHAP Wave 2, the MoCA-SA had
good internal reliability (Cronbach α=0.76). Using item-response models, survey-adapted
items captured a broad range of cognitive abilities and functioned similarly across
gender, education, and ethnic groups. Results demonstrate that the MoCA-SA can be
administered reliably in a survey setting while preserving sensitivity to a broad
range of cognitive abilities and similar performance across demographic subgroups.
</p>
Adult age differences in a variety of cognitive abilities are well documented, and many of those abilities have been found to be related to success in the workplace and in everyday life. However, increased age is seldom associated with lower levels of real-world functioning, and the reasons for this lab-life discrepancy are not well understood. This article briefly reviews research concerned with relations of age to cognition, relations of cognition to successful functioning outside the laboratory, and relations of age to measures of work performance and achievement. The final section discusses several possible explanations for why there are often little or no consequences of age-related cognitive declines in everyday functioning.
The Montreal Cognitive Assessment (MoCA) is an instrument for screening mild cognitive impairment (MCI). This study examined the psychometric properties and the validity of the Taiwan version of the MoCA (MoCA-T) in an elderly outpatient population.
Functional impairment in community-dwelling older adults is common and is associated with poor outcomes. Our goal was to compare the contribution of impairment in executive function or global cognitive function to predicting functional decline and mortality. We studied 7717 elderly women enrolled in a prospective study (mean age 73.3 years) and identified women with poor baseline executive function (score > 1 standard deviation [SD] below the mean on the Trail Making Test B (Trails B; n = 957, 12.4%), poor global cognitive function (score > 1 SD below the mean on a modified Mini-Mental State Examination [mMMSE], n = 387, 5.0%), impairment in both (n = 249, 3.2%), or no impairment (n = 6124, 79.4%). We compared level of functional difficulty (Activities of Daily Living [ADLs] and Instrumental ADLs [IADLs]) at baseline and at 6-year follow-up and survival at follow-up. We also determined if the association was independent of age, education, depression, medical comorbidities, and baseline functional ability. At baseline, women with Trails B impairment only or impairment on both tests reported the highest proportion of ADL and IADL dependence compared to the other groups. At the 6-year follow-up after adjusting for age, education, medical comorbidities, depression, and baseline ADL or IADL, women with only Trails B impairment were 1.3 times more likely to develop an incident ADL dependence (adjusted odds ratio [OR] = 1.34; 95% confidence interval [CI], 1.07-1.69) and 1.5 times more likely to develop a worsening of ADL dependence (adjusted OR = 1.48; 95% CI, 1.16-1.89) when compared to women with no impairment on either test. In addition, women with only Trails B impairment had a 1.5-fold increased risk of mortality (adjusted hazard ratio [HR] = 1.48; 95% CI, 1.21-1.81). In contrast, women with impairment on only mMMSE were not at increased risk to develop incident ADL or IADL dependence, a worsening of ADL or IADL dependence, or mortality. Compared to women with no impairment, women with executive function impairment had significantly worse ADL and IADL function cross-sectionally and over 6 years. Individuals with executive dysfunction also had increased risk of mortality. These results suggest that screening of executive function can help to identify women who are at risk for functional decline and decreased survival.
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