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      Hints for cyclical recruitment of atelectasis during ongoing mechanical ventilation in lavage and oleic acid lung injury detected by SpO₂ oscillations and electrical impedance tomography.

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          Abstract

          Detection of cyclical recruitment of atelectasis after induction of lavage (LAV) or oleic acid injury (OAI) in mechanically ventilated pigs. Primary hypothesis is that oxygen oscillations within the respiratory cycle can be detected by SpO₂ recordings (direct hint). SpO₂ oscillations reflect shunt oscillations that can only be explained by cyclical recruitment of atelectasis. Secondary hypothesis is that electrical impedance tomography (EIT) depicts specific regional changes of lung aeration and of pulmonary mechanical properties (indirect hint).

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          Author and article information

          Journal
          Exp. Lung Res.
          Experimental lung research
          Informa Healthcare
          1521-0499
          0190-2148
          Nov 2014
          : 40
          : 9
          Affiliations
          [1 ] 1Department of Anaesthesiology, University Medical Center Mainz, Mainz, Germany.
          Article
          10.3109/01902148.2014.944719
          25153803
          32f51f65-e68e-412d-a03d-ba422956dbd8
          History

          acute respiratory distress syndrome,animal experiment,lung injury model,non-invasive monitoring,ventilator-induced lung injury

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