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    Review of 'Unlocking drug repurposing clinical trials: resources for investigators'

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    5
    Unlocking drug repurposing clinical trials: resources for investigatorsCrossref
    Excellent summary of Phase II clinical trial types as used in drug repurposing
    Average rating:
        Rated 5 of 5.
    Level of importance:
        Rated 4 of 5.
    Level of validity:
        Rated 5 of 5.
    Level of completeness:
        Rated 5 of 5.
    Level of comprehensibility:
        Rated 5 of 5.
    Competing interests:
    None

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    Unlocking drug repurposing clinical trials: resources for investigators

    Drug repurposing has recently been recognized for its potential to improve the process of drug development. To facilitate the implementation of drug repurposing in clinical research, resources to support investigators in conducting Phase II repurposing trials are under development, which will be presented as part of a comprehensive platform. Innovative clinical trial designs and mechanism-based network pharmacology are also emphasized.
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      Review information

      10.14293/S2199-1006.1.SOR-LIFE.ANE16N.v1.ROIIZT
      This work has been published open access under Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com.

      Life sciences
      Mechanism-based network pharmacology,Investigator initiated trials,Drug repurposing,Phase II clinical trials,Innovative clinical trial designs

      Review text

      This is a very good top-level summary of what clinical Phase II trials in drug repurposing are, and how REPO4EU uses them to achieve its objectives.. We can publish it in its present version.

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